CVE-2026-31968 HIGH

CVE-2026-31968: HTSlib CRAM decoder vulnerable to buffer overflow

Vendor Samtools
Product htslib
Weakness CWE-121
Published March 18, 2026
Last update March 18, 2026

CVSS base score

8.8/10
Attack vector Network
Attack complexity Low
Privileges required None
User interaction None
Confidentiality
Integrity

CVSS vector

CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:L/SC:N/SI:N/SA:N

What the vulnerability does

01Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. For the `VARINT` and `CONST` encodings, incomplete validation of the context in which the encodings were used could result in up to eight bytes being written beyond the end of a heap allocation, or up to eight bytes being written to the location of a one byte variable on the stack, possibly causing the values to adjacent variables to change unexpectedly. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Key dates

02Disclosure timeline

March 18, 2026 CVE published
March 18, 2026 Record updated